The fight against aging and age-related changes in the face and body skin in particular is one of the most topical areas of the current esthetic medicine. Age-related changes may affect any skin layer, and its aging is promoted by endogenous and exogenous factors. For instance, reduced levels of collagen and elastin in the dermis promote line formation; therefore, products that could boost the synthesis of the two proteins are widely used. To treat age-related changes in various areas of the face and body, the following techniques are used: surgery, energy-based devices, thread technologies, contouring and volumizing with dermal fillers, botulinum toxin, biorevitalizants, collagen-stimulating therapy, in particular, poly-L-lactic acid (poly-L-lactic acid, PLLA), the mechanism of action of which is aimed at stimulating neocollagenesis. PLLA has a long history of use, from surgical suture material in the 1970s and lipoatrophy correction at the end of the past century to correction of age-related changes in different locations nowadays. Today, esthetic physicians use PLLA as a volumizer and a skin quality enhancer. There are literature data evidencing the efficacy and safety of PLLA used for correction of age-related changes alone and in combination with other products or esthetic medical device procedures. In this paper, we describe an optimal way of using PLLA to minimize adverse events and share the injection techniques of PLLA for various locations in the face and body.

Keywords. poly-L-lactic acid, cosmetology, fillers, aging